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KMID : 0604520010270010073
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Journal of the Society of Cosmetic Scientists of Korea
2001 Volume.27 No. 1 p.73 ~ p.82
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Inhibitory effects of prunus persica flower extracts on UV-induced skin damage
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이강태/Lee KT
유영경/김성우/정지헌/조병기/김영하/양혜은/허문영/김현표/Yoo YK/Kim SW/Jeong JH/Jo BK/Kim YH/Yang HE/Heo MY/Kim HP
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Abstract
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For an attempt to develop safe materials protecting UV-induced skin damage, plant extracts were evaluated for their antioxidative and free radical scavenging activities. From the results of these screening procedures, the ethanol extract of the flowers of Prunus persica was selected for further study. It was found that Prunus persica (50-200 ㎍/ml) inhibited UVB-induced DNA damage measured by tail moment in the Single Cell Gel Electrophoresis(COMET assay) and inhibited UV-induced lipid peroxidation, especially against UVB-induced peroxidation at higher than 10 ㎍/ml. Also P. persica(100~1,000 ㎍/ml) inhibited the amount of 14C-arachidonic acid metabolites release from UVB-irradiated keratinocytes and it possessed the protective activity against UV-induced cytotoxicity of keratinocytes. All these results indicate that the flowers of P. persica extract may be beneficial for protection UV-induced skin damage when topically applied.
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